To share the experience of dealing with Kuwaiti children suffering from celiac disease
Retrospective research 47 patients of CD serology and biopsy proven (symptomatic: 25, screened: 22) Age range from 7 to 189 months
EMA, AGA-IgA, AGA-IgG, and anti-tTG
66% females, 34% males, 85% EMA positive, 79% AGA-IgA positive, and 77% AGA-IgG positive. 19 have T1D, 2 have Down’s syndrome, 1 has both T1D and Down’s syndrome, 3 have hypothyroidism, and 1 juvenile has idiopathic arthritis 9% had celiac disease family history.
To identify the clinical pattern of celiac disease prevalence
Retrospective, hospital-based research
Anti-tTG, IgA, IgG antibodies and biopsy proven
80 children were diagnosed with celiac disease (age range of 0.5–18 years) 39 (49%) individuals showed conventional symptoms of malabsorption, while 41 (51%) were found to be at high risk of developing CD.
18 (23%) = positive IgG antibodies
11 out of 65 individuals showed disturbed liver function tests.
To address clinical characteristics of celiac disease among Saudi children as well as to examine the adherence rate to gluten-free diet along with its determinant factors
Cross-sectional study 113 children; median age 9.9 years
Biopsy-confirmed cases
92% of the patients were symptomatic while 8% were asymptomatic. Out of total, 62 of the children were females. The most commonly presenting symptoms include poor weight gain (54%), chronic abdominal pain (59.3%), abdominal distention, gases, bloating (46.1%), and chronic diarrhea (41.6%). Shorter duration since the diagnosis and younger age at diagnosis were interrelated with an improved adherence rate.
To characterize the clinical presentations and diagnosis in children under the age of 18 with celiac disease at a private tertiary care health care center in Riyadh
Retrospective study 59 children
IgA-tTG and IgG-tTG antibodies and biopsy
50.8% males Median age 8 years Mean duration of symptoms before diagnosis 2.3 years (±1.5). Classical disease was merely observed in 30.5%, while 69.5% had either nonclassical presentations or belonged to high-risk groups for celiac disease 91.5% positive for IgA-tTG antibodies 81.3% positive for IgG-tTG 52 had Marsh grade III lesion.
