Comprehensive Bioinformatics Analysis Reveals Hub Genes and Inflammation State of Rheumatoid Arthritis

Table 1

GO analysis results of DEGs (top 8 terms of each category were listed).

Ontology	ID	Description	Adj. value	Count
BP	GO:0050900	Leukocyte migration	2.33E-08	18
BP	GO:0050851	Antigen receptor-mediated signaling pathway	2.33E-08	15
BP	GO:0002449	Lymphocyte mediated immunity	6.91E-08	15
BP	GO:0051249	Regulation of lymphocyte activation	6.91E-08	17
BP	GO:0050853	B cell receptor signaling pathway	2.54E-07	10
BP	GO:0002429	Immune response-activating cell surface receptor signaling pathway	3.05E-07	16
BP	GO:0030098	Lymphocyte differentiation	4.36E-07	14
BP	GO:0006959	Humoral immune response	4.36E-07	14
CC	GO:0009897	External side of plasma membrane	1.28E-08	17
CC	GO:0042571	Immunoglobulin complex, circulating	7.02E-06	7
CC	GO:0019814	Immunoglobulin complex	8.86E-06	9
CC	GO:0042101	T cell receptor complex	0.008265	5
CC	GO:0001772	Immunological synapse	0.012398	3
CC	GO:0072562	Blood microparticle	0.012678	5
CC	GO:0042613	MHC class II protein complex	0.030215	2
CC	GO:0098802	Plasma membrane receptor complex	0.033455	6
MF	GO:0034987	Immunoglobulin receptor binding	8.86E-06	7
MF	GO:0008009	Chemokine activity	1.34E-05	6
MF	GO:0045236	CXCR chemokine receptor binding	1.51E-05	4
MF	GO:0042379	Chemokine receptor binding	5.51E-05	6
MF	GO:0003823	Antigen binding	7.28E-05	8
MF	GO:0005125	Cytokine activity	7.80E-05	9
MF	GO:0048018	Receptor ligand activity	0.000201	12
MF	GO:0001664	G protein-coupled receptor binding	0.002229	8