Use Chou’s 5-Step Rule to Predict DNA-Binding Proteins with Evolutionary Information

Table 4

The performance of the method and other existing methods on the PDB186 dataset.

Methods	ACC (%)	MCC	SN (%)	SP (%)
IDNA-Prot|dis	72.0	0.445	79.5	64.5
IDNA-Prot	67.2	0.344	67.7	66.7
DNA-Prot	61.8	0.240	69.9	53.8
DNAbinder	60.8	0.216	57.0	64.5
DNABIND	67.7	0.355	66.7	68.8
DNA-Threader	59.7	0.279	23.7	95.7
DBPPred	76.9	0.538	79.6	74.2
IDNAPro-PseAAC-EL	71.5	0.442	82.8	60.2
Kmer1+ACC	71.0	0.431	82.8	59.1
RF-based method	79.0	0.616	95.7	62.4
SVM-based method	75.3	0.560	96.8	53.8