Research Article

Comparing the Effect of Combining Exercise with Rosuvastatin versus Atorvastatin on Lipid Profile and Functional Capacity: A Retrospective Cohort Study

Table 1

Characteristics of patients included in the analyses according to statin type used.

Sociodemographic and clinical variables measured at admissionAtorvastatin users
(106 patients)
Rosuvastatin users
(176 patients)
value
No. (%) or No. (%) or

Age (years)0.94
Sex (male)75 (70.8)120 (68.2)0.68
Tobacco smoking
 Nonsmoker54 (51.4)83 (47.7)0.54
 Previous smoker42 (40.0)78 (44.8)0.43
 Current smoker9 (8.6)13 (7.5)0.74
Weight (kg)0.16
Blood pressure (mmHg)
 Systolic BP0.18
 Diastolic BP1.0
Lipids (mmol/L)
 Total cholesterol0.39
 Triglycerides0.14
 LDL0.002
 HDL0.03
HbA1c (mmol/mol)0.95
HbA1c (%)0.95
6-minute walk test (meters)0.75
SF-36 score0.42
Medications used
 Cardiovascular medications102 (96.2)163 (92.6)0.22
 Anticoagulants18 (17.0)24 (13.6)0.44
 Antiplatelets91 (85.9)148 (84.1)0.68
 Other cholesterol-lowering medications7 (6.6)18 (10.2)0.30
 Oral antidiabetics22 (20.8)47 (26.7)0.26
 Insulin7 (6.6)16 (9.1)0.46
Statin doses
 Low to moderate intensity33 (31.1)72 (40.9)0.09
 High intensity73 (68.9)104 (59.1)0.09
Exercise performed during the 12-week cardiac rehabilitation program
 Total minutes of exercise0.61
 Adherence (%) to exercise schedule (weekly sessions performed/prescribed)0.05
 Average of weekly exercise minutes0.69

HbA1c: glycated haemoglobin; SF-36: 36-Item Short-Form Health Survey; LDL: low-density lipoprotein; HDL: high-density lipoprotein; BP: blood pressure. Stone et al. [8].