Comparing the Effect of Combining Exercise with Rosuvastatin versus Atorvastatin on Lipid Profile and Functional Capacity: A Retrospective Cohort Study
Table 2
Crude and adjusted linear regression coefficients and 95% confidence intervals for changes in total cholesterol.
Variable
Change in total cholesterol
Crude model
Simple interaction model
Fully adjusted model
95% CI
95% CI
95% CI
Intercept
NA
NA
0.059
(-0.209, 0.328)
0.660
(-1.497, 2.818)
Atorvastatin use (yes)
Reference
Reference
Reference
Reference
Reference
Reference
Rosuvastatin use (yes)
0.026
(-0.134, -0.186)
-0.133
(-0.505, 0.239)
-0.612
(-1.177, -0.478)
Average exercise minutes/week (minutes)
-0.0001
(-0.001, 0.001)
-0.001
(-0.003, 0.001)
-0.002
(-0.005, 0.001)
Rosuvastatin use Average exercise interaction
NA
NA
0.001
(-0.001, 0.004)
0.004
(0.001, 0.008)
Age (years)
0.002
(-0.007, 0.011)
NA
NA
-0.002
(-0.018, 0.014)
Sex (male)
0.084
(-0.078, 0.247)
NA
NA
0.267
(-0.063, 0.596)
Tobacco smoking (previous/current smoker)
-0.005
(-0.135, 0.125)
NA
NA
-0.089
(-0.321, 0.142)
Other cholesterol-lowering medications (yes)
0.117
(-0.160, 0.394)
NA
NA
0.147
(-0.300, 0.595)
Anticoagulants (yes)
-0.012
(-0.242, 0.217)
NA
NA
-0.220
(-0.730, 0.289)
Antiplatelets (yes)
0.158
(-0.066, 0.382)
NA
NA
-0.143
(-0.596, 0.310)
Cardiovascular medications (yes)
0.159
(-0.169, 0.488)
NA
NA
0.213
(-0.229, 0.656)
Oral antidiabetics (yes)
-0.004
(-0.188, 0.181)
NA
NA
0.094
(-0.196, 0.383)
Insulin (yes)
-0.125
(-0.454, 0.203)
NA
NA
-0.455
(-0.956, 0.047)
Adherence (%) to exercise schedule (weekly sessions performed/prescribed)
