Comparing the Effect of Combining Exercise with Rosuvastatin versus Atorvastatin on Lipid Profile and Functional Capacity: A Retrospective Cohort Study
Table 3
Crude and adjusted linear regression coefficients and 95% confidence intervals for changes in LDL.
Variable
Change in LDL
Crude model
Simple interaction model
Fully adjusted model
95% CI
95% CI
95% CI
Intercept
NA
NA
0.159
(-0.041, 0.349)
0.804
(-0.623, 2.232)
Atorvastatin use (yes)
Reference
Reference
Reference
Reference
Reference
Reference
Rosuvastatin use (yes)
0.002
(-0.113, 0.118)
-0.179
(-0.449, 0.089)
-0.518
(-0.902, -0.134)
Average exercise minutes/week (minutes)
-0.0004
(-0.001, 0.001)
-0.001
(-0.002, 0.001)
-0.002
(-0.004, -0.001)
Rosuvastatin use Average exercise interaction
NA
NA
0.001
(-0.001, 0.003)
0.004
(0.001, 0.007)
Age (years)
0.0001
(-0.006, 0.006)
NA
NA
0.005
(-0.006, 0.015)
Sex (male)
0.074
(-0.043, 0.191)
NA
NA
0.275
(0.057, 0.493)
Tobacco smoking (previous/current smoker)
0.004
(-0.094, 0.101)
NA
NA
0.003
(-0.161, 0.167)
Other cholesterol-lowering medications (yes)
0.033
(-0.167, 0.233)
NA
NA
0.099
(-0.197, 0.396)
Anticoagulants (yes)
0.031
(-0.134, 0.197)
NA
NA
-0.205
(-0.548, 0.138)
Antiplatelets (yes)
0.099
(-0.065, 0.264)
NA
NA
-0.124
(-0.430, 0.182)
Cardiovascular medications (yes)
-0.033
(-0.269, 0.204)
NA
NA
-0.079
(-0.371, 0.214)
Oral antidiabetics (yes)
0.005
(-0.128, 0.138)
NA
NA
0.049
(-0.144, 0.241)
Insulin (yes)
-0.025
(-0.275, 0.226)
NA
NA
-0.245
(-0.599, 0.109)
Adherence (%) to exercise schedule (weekly sessions performed/prescribed)
