Comparing the Effect of Combining Exercise with Rosuvastatin versus Atorvastatin on Lipid Profile and Functional Capacity: A Retrospective Cohort Study
Table 4
Crude and adjusted linear regression coefficients and 95% confidence intervals for changes in HDL.
Variable
Change in HDL
Crude model
Simple interaction model
Fully adjusted model
95% CI
95% CI
95% CI
Intercept
NA
NA
-0.029
(-0.124, 0.066)
0.326
(-0.354, 1.007)
Atorvastatin use (yes)
Reference
Reference
Reference
Reference
Reference
Reference
Rosuvastatin use (yes)
-0.036
(-0.093, 0.022)
0.013
(-0.119, 0.145)
0.016
(-0.162, 0.194)
Average exercise minutes/week (minutes)
0.001
(0.0005, 0.001)
0.001
(0.0001, 0.001)
0.001
(0.0001, 0.002)
Rosuvastatin use Average exercise interaction
NA
NA
-0.0004
(-0.001, 0.001)
-0.0004
(-0.002, 0.001)
Age (years)
0.001
(-0.002, 0.004)
NA
NA
0.001
(-0.004, 0.006)
Sex (male)
0.029
(-0.294, 0.088)
NA
NA
0.058
(-0.046, 0.162)
Tobacco smoking (previous/current smoker)
0.035
(-0.011, 0.082)
NA
NA
0.034
(-0.039, 0.107)
Other cholesterol-lowering medications (yes)
0.012
(-0.089, 0.112)
NA
NA
0.045
(-0.096, 0.186)
Anticoagulants (yes)
-0.084
(-0.164, -0.004)
NA
NA
-0.083
(-0.244, 0.078)
Antiplatelets (yes)
0.037
(-0.044, 0.119)
NA
NA
0.002
(-0.141, 0.145)
Cardiovascular medications (yes)
0.115
(-0.002, 0.233)
NA
NA
0.051
(-0.089, 0.190)
Oral antidiabetics (yes)
-0.029
(-0.095, 0.038)
NA
NA
0.015
(-0.076, 0.106)
Insulin (yes)
-0.070
(-0.189, 0.048)
NA
NA
-0.102
(-0.260, 0.056)
Adherence (%) to exercise schedule (weekly sessions performed/prescribed)