Comparing the Effect of Combining Exercise with Rosuvastatin versus Atorvastatin on Lipid Profile and Functional Capacity: A Retrospective Cohort Study
Table 6
Crude and adjusted linear regression coefficients and 95% confidence intervals for changes in 6MWT.
Variable
Change in 6MWT
Crude model
Simple interaction model
Fully adjusted model
95% CI
95% CI
95% CI
Intercept
NA
NA
5.131
(-24.940, 35.202)
114.935
(-19.333, 249.202)
Atorvastatin use (yes)
Reference
Reference
Reference
Reference
Reference
Reference
Rosuvastatin use (yes)
36.440
(18.090, 54.791)
47.328
(5.589, 89.067)
46.021
(2.866, 89.176)
Average exercise minutes/week (minutes)
-0.062
(-0.225, 0.102)
0.004
(-0.204, 0.212)
-0.082
(-0.297, 0.134)
Rosuvastatin use Average exercise interaction
NA
NA
-0.094
(-0.408, 0.219)
-0.043
(-0.363, 0.277)
Age (years)
-0.298
(-1.243, 0.647)
NA
NA
-0.009
(-1.067, 1.049)
Sex (male)
9.749
(-9.798, 29.295)
NA
NA
14.808
(-7.148, 36.763)
Tobacco smoking (previous/current smoker)
-1.037
(-16.426, 14.352)
NA
NA
1.571
(-14.644, 17.787)
Other cholesterol-lowering medications (yes)
5.982
(-25.776, 37.741)
NA
NA
9.326
(-21.640, 40.293)
Anticoagulants (yes)
-3.371
(-32.859, 26.118)
NA
NA
-7.992
(-40.845, 24.860)
Antiplatelets (yes)
12.388
(-19.310, 44.086)
NA
NA
16.740
(-19.159, 52.640)
Cardiovascular medications (yes)
-14.115
(-50.799, 22.569)
NA
NA
-9.581
(-47.003, 27.842)
Oral antidiabetics (yes)
-31.361
(-51.964, -10.757)
NA
NA
-25.519
(-47.835, -3.203)
Insulin (yes)
-19.058
(-53.710, 15.593)
NA
NA
-10.874
(-45.502, 23.753)
Adherence (%) to exercise schedule (weekly sessions performed/prescribed)
