Changes of miRNA Expression Profiles from Cervical-Vaginal Fluid-Derived Exosomes in Response to HPV16 Infection

Figure 2

Differentially expressed miRNAs in exosomes of HPV16-infected CVF and control samples. (a) Upregulated or downregulated miRNAs were marked in red or blue, respectively. The number of all conserved miRNAs located in the human chromosomes was shown in the histogram. The circular diagram on the right represents total conserved miRNAs in the human chromosome, with 1293 upregulated and 1255 downregulated. Heatmap analysis showing the fold change of the top 15 (b) highest and C. lowest miRNAs in the HPV16-infected group. Color scale is from -1.25 (blue, lower than mean) to 2.41 (red, higher than the mean). Each column represents one sample, and each row indicates a transcript.

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