Associated Targets of the Antioxidant Cardioprotection of Ganoderma lucidum in Diabetic Cardiomyopathy by Using Open Targets Platform: A Systematic Review

Table 3

mTOR score association with 49 heart diseases.

No.	Heart disease	Association score
		Data types; Genetic	Data types; Known drug	Data types; Literature	Data types; Animal model	Overall
1	Heart disease	0.00041	0.79550	0.14161	0.19028	0.8588
2	Cardiomyopathy	0.00000	0.77847	0.11930	0.19028	0.8393
3	Hypertrophic cardiomyopathy	0.00000	0.77222	0.10214	0.00000	0.7978
4	Heart failure	0.00000	0.25000	0.05235	0.00000	0.2631
5	Dilated cardiomyopathy	0.00000	0.00000	0.07568	0.19028	0.2092
6	Congestive heart failure	0.00000	0.20000	0.02636	0.00000	0.2066
7	Diastolic heart failure	0.00000	0.20000	0.00000	0.00000	0.2000
8	Barth syndrome	0.00000	0.00000	0.00000	0.19028	0.1903
9	Coronary heart disease	0.00000	0.00000	0.12009	0.00000	0.1201
10	Diabetic cardiomyopathy	0.00000	0.10000	0.05391	0.00000	0.1135
11	Coronary artery disease	0.00000	0.00000	0.10961	0.00000	0.1096
12	Systemic scleroderma	0.00000	0.00000	0.09914	0.00000	0.0991
13	Cardiotoxicity	0.00000	0.00000	0.09016	0.00000	0.0902
14	Glycogen storage disease due to acid maltase deficiency	0.00000	0.00000	0.08380	0.00000	0.0838
15	Myocardial infarction	0.00000	0.00000	0.06467	0.00000	0.0647
16	Persistent truncus arteriosus	0.00000	0.00000	0.06144	0.00000	0.0614
17	Heart neoplasm	0.00000	0.00000	0.06126	0.00000	0.0613
18	Emery-Dreifuss muscular dystrophy	0.00000	0.00000	0.05780	0.00000	0.0578
19	Ischemia reperfusion injury	0.00000	0.00000	0.05702	0.00000	0.0570
20	Myocardial ischemia	0.00000	0.00000	0.05658	0.00000	0.0566
21	Carney complex	0.00000	0.00000	0.05494	0.00000	0.0549
22	Down syndrome	0.00000	0.00000	0.05488	0.00000	0.0549
23	Cardiac rhabdomyoma	0.00000	0.00000	0.05475	0.00000	0.0547
24	Autosomal dominant Emery-Dreifuss muscular dystrophy	0.00000	0.00000	0.05280	0.00000	0.0528
25	Polyarteritis nodosa	0.00000	0.00000	0.04343	0.00000	0.0434
26	Steinert myotonic dystrophy	0.00000	0.00000	0.04273	0.00000	0.0427
27	Acute myocardial infarction	0.00000	0.00000	0.03798	0.00000	0.0380
28	Cardiac arrhythmia	0.00041	0.00000	0.03721	0.00000	0.0373
29	Myocarditis	0.00000	0.00000	0.03263	0.00000	0.0326
30	Duchenne muscular dystrophy	0.00000	0.00000	0.03253	0.00000	0.0325
31	Gaucher disease	0.00000	0.00000	0.03230	0.00000	0.0323
32	Cardiac arrest	0.00000	0.00000	0.02847	0.00000	0.0285
33	Atrial fibrillation	0.00000	0.00000	0.02720	0.00000	0.0272
34	Aortic stenosis	0.00000	0.00000	0.01910	0.00000	0.0191
35	Acute coronary syndrome	0.00000	0.00000	0.01900	0.00000	0.0190
36	Sleep disorder	0.00000	0.00000	0.01840	0.00000	0.0184
37	Williams syndrome	0.00000	0.00000	0.01640	0.00000	0.0164
38	Supravalvular aortic stenosis	0.00000	0.00000	0.01640	0.00000	0.0164
39	Autoimmune myocarditis	0.00000	0.00000	0.01560	0.00000	0.0156
40	Friedreich ataxia	0.00000	0.00000	0.01480	0.00000	0.0148
41	Obstructive sleep apnea	0.00000	0.00000	0.01480	0.00000	0.0148
42	PHACE syndrome	0.00000	0.00000	0.01440	0.00000	0.0144
43	Glycogen storage disease due to LAMP-2 deficiency	0.00000	0.00000	0.01440	0.00000	0.0144
44	Idiopathic pulmonary arterial hypertension	0.00000	0.00000	0.01400	0.00000	0.0140
45	Fabry disease	0.00000	0.00000	0.01340	0.00000	0.0134
46	Becker muscular dystrophy	0.00000	0.00000	0.00840	0.00000	0.0084
47	Hemopericardium	0.00000	0.00000	0.00720	0.00000	0.0072
48	Aortic coarctation	0.00000	0.00000	0.00680	0.00000	0.0068
49	Atrial flutter	0.00041	0.00000	0.00000	0.00000	0.0004