Profiling and Bioinformatics Analysis of Differentially Expressed circRNAs in Spinal Ligament Tissues of Patients with Ankylosing Spondylitis

Table 2

The top 10 circRNAs with the significant upregulation or downregulation.

Position	circBankID	circBaseID	Gene symbol	Length	Type	log2FC	value		Regulation
chr11_92085261_92088570_+	hsa_circFAT3_006	hsa_circ_0000348	FAT3	3309	Exon-exon	3.7819	0.0000	0.0058	Up
chr13_76195898_76335174_+	NA	NA	LMO7	NA	Exon-exon	3.1527	0.0005	0.0639	Up
chrX_147743428_147744289_+	hsa_circAFF2_005	hsa_circ_0001947	AFF2	861	Exon-exon	2.9490	0.0000	0.0000	Up
chr8_13356557_13357705_-	hsa_circDLC1_002	hsa_circ_0135780	DLC1	1148	Exon-exon	2.3865	0.0005	0.0639	Up
chr2_200233327_200298237_-	hsa_circSATB2_015	hsa_circ_0003915	SATB2	531	Exon-exon	2.2778	0.0013	0.1144	Up
chr9_4286037_4286523_-	hsa_circGLIS3_003	hsa_circ_0002874	GLIS3	486	Exon-exon	2.1186	0.0000	0.0047	Up
chr12_122825299_122826244_-	hsa_circCLIP1_019	hsa_circ_0029069	CLIP1	945	Exon-exon	2.0273	0.0001	0.0123	Up
chr3_18419661_18462483_-	hsa_circSATB1_004	hsa_circ_0064555	SATB1	1599	Exon-exon	1.9818	0.0084	0.2278	Up
chr21_36206706_36231875_-	hsa_circRUNX1_005	hsa_circ_0002360	RUNX1	297	Exon-exon	1.8979	0.0066	0.2154	Up
chr9_37424841_37426651_+	hsa_circGRHPR_002	hsa_circ_0001861	GRHPR	321	Exon-exon	1.8159	0.0008	0.0828	Up
chr6_144858717_144864006_+	hsa_circUTRN_065	hsa_circ_0130908	UTRN	362	Exon-exon	-2.1886	0.0082	0.2278	Down
chr19_4511522_4511918_-	NA	NA	PLIN4	NA	Exon-exon	-2.1979	0.0022	0.1357	Down
chr8_17570722_17581342_-	hsa_circMTUS1_004	hsa_circ_0083443	MTUS1	336	Exon-exon	-2.3338	0.0032	0.1500	Down
chr5_102432244_102433485_-	hsa_circGIN1_005	hsa_circ_0006499	GIN1	655	Exon-exon	-2.6637	0.0019	0.1295	Down
chr1_154207066_154207767_+	hsa_circUBAP2L_011	hsa_circ_0110845	UBAP2L	298	Exon-exon	-3.1140	0.0027	0.1426	Down
chr9_14120438_14179779_-	hsa_circNFIB_012	hsa_circ_0138300	NFIB	683	Exon-exon	-3.1464	0.0002	0.0326	Down
chr10_34558584_34573173_-	hsa_circPARD3_036	hsa_circ_0018168	PARD3	354	Exon-exon	-3.1686	0.0020	0.1295	Down
chr3_100565215_100581229_-	hsa_circABI3BP_001	hsa_circ_0121334	ABI3BP	513	Exon-exon	-3.4042	0.0000	0.0000	Down
chr3_100565215_100570784_-	NA	NA	ABI3BP	NA	Exon-exon	-4.1847	0.0000	0.0000	Down
chr17_58012553_58018304_+	NA	NA	RPS6KB1	NA	Exon-exon	-5.5909	0.0000	0.0079	Down

Position: chromosome location of circRNA; log2FC: log2Fold change; : adjusted value; NA: not available.