Effect of a DPP-4 Inhibitor on Orthodontic Tooth Movement and Associated Root Resorption

Figure 1

Orthodontic appliance and effect of DPP-4 inhibitor on orthodontic tooth movement. (a) Intraoral photograph of the appliance fixed between incisor and first molar. (b) Photograph of the silicone impression with stereoscopic microscope after tooth movement. The dashed line connecting the central fossae of the first and second molars was used to measure the distance from the distal marginal ridge of the first molar to the mesial marginal ridge of the second molar. (red double arrow). (c) Intraoral photographs of the upper left molars after 12 days of tooth movement with administration of PBS or 30 μg of DPP-4 inhibitor, and the control (unloaded). Tooth movement distances were measured by taking silicone impressions. . (d) Comparison of tooth movement among the three groups. for each group. .

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