Effect of a DPP-4 Inhibitor on Orthodontic Tooth Movement and Associated Root Resorption

Figure 2

Histology analysis of mouse alveolar bone in the maxillary left first molar area in horizontal sections. (a) TRAP-stained histological sections of the distobuccal root of the maxillary left first molar before and after 12 days of experimental tooth movement with administration of PBS or 30 μg of DPP-4 inhibitor. Arrows represent the direction of orthodontic tooth movement. (b) Evaluation of the number of TRAP-positive multinucleated cells on the mesial side of the distobuccal upper-left first molar. for each group. .

(a)

(b)