BioMed Research International

Clinical Study

The Prognosis Analysis of Liver Cirrhosis with Acute Variceal Bleeding and Validation of Current Prognostic Models: A Large Scale Retrospective Cohort Study

Table 1

Demographic, clinical, and biochemical characteristics in patients with acute gastrointestinal bleeding ().
N
Age () () (range 14-89)
Sex (male)224 (59.1%)
Cause of cirrhosis
 Hepatic B virus205 (54.1%)
 Hepatic C virus30 (7.9%)
 Both hepatic B and C virus2 (0.5%)
 Autoimmune liver disease42 (11.1%)
 Alcoholic9 (2.4%)
 Other91 (24%)
History of GIB86 (22.7%)
Ascites229 (60.4%)
Hepatic encephalopathy9 (2.4%)
Hepatocellular carcinoma72 (19%)
Baseline laboratory values, (range)
 White blood cell (×109/L) (0.93-64.86)
 Platelet (×109/L) (1-511)
 Red blood cell (×109/L) (1.2-5.4)
 Hemoglobin (g/L) (23-105)
Albumin (g/dL) (14.5-55)
 Total serum bilirubin (μmol/L) (2.3-662.4)
 Serum creatinine (μmol/L) (11-513)
 International normalized ratio (0.97-1.74)
 Alanine aminotransferase (U/L) (2.4-734)
 Aspartate aminotransferase (U/L) (8-1244)
 Alkaline phosphatase (U/L) (10-1425)
 Gamma-glutamyl transpeptidase (U/L) (4.4-3331)
 Prothrombin time (s) (1.2-80)
 α-Fetoprotein (ng/mL) (0.19-287000)
 Absolute neutrophil count (×109/L) (0.5-58.8)
 Absolute lymphocyte count (×109/L) (-10.4)
Child-Pugh
 A112 (29.6%)
 B205 (54.1%)
 C62 (16.4%)
Child-Pugh score (5-13)
MELD score (5.06-11.9)
NLR score (0.3-101.4)
CAGIB score (-7.8-1.6)
In-hospital death25 (6.6%)
MELD: model for end-stage liver disease; NLR: neutrophil to lymphocyte ratio; CAGIB: cirrhosis acute gastrointestinal bleeding.