Three-Dimensional-Printed Poly-L-Lactic Acid Scaffolds with Different Pore Sizes Influence Periosteal Distraction Osteogenesis of a Rabbit Skull

Figure 3

Construction of the in vivo bioreactor. (a) Separate the skin and periosteum on the rabbit skull. (b) The PLLA scaffold was fixed on the skull bone by two self-drilling screws under the periosteum. (c) Suture the periosteum in situ after covering the whole distraction scaffold. (d) Seven days later, a self-tapping screw was applied to uplift the PLLA scaffold to distract the periosteum.

(a)

(b)

(c)

(d)