Exosomes Derived from Brain Metastatic Breast Cancer Cells Destroy the Blood-Brain Barrier by Carrying lncRNA GS1-600G8.5

Figure 2

Establishment of the in vitro BBB system. (a) Schematic diagram showing the construction of the in vitro BBB model, using human brain microvascular endothelium cell (BMEC), brain pericytes, and astrocytes. (b) Transepithelial/transendothelial electrical resistance (TEER) detection in the BBB model. (c) Permeability of the BBB model. The permeability of a cell-free system was used as the control. (d) Schematic diagram displayed the methods for detecting exosome effects on invasion of breast cancer cells through the BBB model.

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