Leptin Overexpression as a Poor Prognostic Factor for Colorectal Cancer

Table 2

Cox analyses of potential prognostic factors for overall survival in CRC.

Factor	Comparison	Univariate analysis			Multivariate analysis
		HR	95% CI	value	HR	95% CI	value
Lymph node involvement	Yes vs. no	1.649	1.068-2.369	0.021	1.423	0.976-1.743	0.053
M stage	M1 vs. M0	2.137	1.936-4.312	0.004	2.437	1.692-3.175	0.002
Leptin expression	High vs. low	2.034	1.912-3.425	0.007	2.011	1.279-2.231	0.017

HR: hazard ratio; CI: confidence interval.