Circulating Cytokines and Lymphocyte Subsets in Patients Who Have Recovered from COVID-19

Table 4

Correlation analysis between lymphocyte subsets and cytokines in two-week postrecovery patients.

Analyses		Cytokines (pg/mL)							Lymphocyte subsets (per/μL)
		IL-2	IL-4	IL-6	IL-10	TNF-α	INF-γ	IL-17	Total lymphocyte	CD3^+ T cell	CD3^+CD4^+ T cell	CD3^+CD8^+ T cell	CD19^+ B cell	CD56^+ NK cell	CD4^+/CD8^+
IL-2		1	0.112	0.056	0.147	-0.155	0.24	-0.095	0.281	0.299	0.148	0.38	0.031	-0.069	-0.048
		0	0.536	0.757	0.414	0.39	0.179	0.6	0.113	0.092	0.411	0.029	0.863	0.703	0.793
IL-4		0.112	1	-0.254	0.273	-0.074	0.082	0.628	0.095	0.164	0.154	0.175	0.088	-0.109	0.002
		0.536	0	0.154	0.124	0.684	0.649	0	0.599	0.361	0.393	0.331	0.627	0.545	0.991
IL-6		0.056	-0.254	1	-0.081	0.371	-0.119	-0.394	0.13	0.023	0.123	0.034	0.219	0.177	-0.001
		0.757	0.154	0	0.655	0.033	0.509	0.023	0.47	0.899	0.496	0.852	0.221	0.323	0.994
IL-10		0.147	0.273	-0.081	1	-0.177	0.04	0.219	-0.012	-0.041	-0.168	0.204	-0.088	0.16	-0.242
		0.414	0.124	0.655	0	0.325	0.827	0.22	0.949	0.822	0.349	0.255	0.627	0.375	0.175
TNF-α		-0.155	-0.074	0.371	-0.177	1	-0.322	-0.464	0.106	0.148	0.112	0.272	-0.149	-0.139	-0.104
		0.39	0.684	0.033	0.325	0	0.067	0.006	0.558	0.412	0.534	0.125	0.409	0.44	0.563
INF-γ		0.24	0.082	-0.119	0.04	-0.322	1	-0.002	-0.231	-0.225	-0.191	-0.201	-0.194	-0.059	0.09
		0.179	0.649	0.509	0.827	0.067	0	0.99	0.197	0.208	0.287	0.261	0.279	0.743	0.617
IL-17		-0.095	0.628	-0.394	0.219	-0.464	-0.002	1	-0.088	-0.012	0.088	-0.129	0.04	-0.111	0.124
		0.6	0	0.023	0.22	0.006	0.99	0	0.624	0.949	0.625	0.474	0.826	0.539	0.492
Total lymphocyte		0.281	0.095	0.13	-0.012	0.106	-0.231	-0.088	1	0.945	0.891	0.762	0.736	0.284	0.381
		0.113	0.599	0.47	0.949	0.558	0.197	0.624	0	0	0	0	0	0.11	0.029
CD3^+ T cell		0.299	0.164	0.023	-0.041	0.148	-0.225	-0.012	0.945	1	0.913	0.82	0.631	0.04	0.386
		0.092	0.361	0.899	0.822	0.412	0.208	0.949	0	0	0	0	0	0.827	0.027
CD3^+CD4^+ T cell		0.148	0.154	0.123	-0.168	0.112	-0.191	0.088	0.891	0.913	1	0.608	0.721	0.022	0.605
		0.411	0.393	0.496	0.349	0.534	0.287	0.625	0	0	0	0	0	0.905	0
CD3^+CD8^+ T cell		0.38	0.175	0.034	0.204	0.272	-0.201	-0.129	0.762	0.82	0.608	1	0.34	0.1	-0.127
		0.029	0.331	0.852	0.255	0.125	0.261	0.474	0	0	0	0	0.053	0.582	0.481
CD19^+ B cell		0.031	0.088	0.219	-0.088	-0.149	-0.194	0.04	0.736	0.631	0.721	0.34	1	0.309	0.495
		0.863	0.627	0.221	0.627	0.409	0.279	0.826	0	0	0	0.053	0	0.08	0.003
CD56^+ NK cell		-0.069	-0.109	0.177	0.16	-0.139	-0.059	-0.111	0.284	0.04	0.022	0.1	0.309	1	-0.103
		0.703	0.545	0.323	0.375	0.44	0.743	0.539	0.11	0.827	0.905	0.582	0.08	0	0.568
CD4^+/CD8^+		-0.048	0.002	-0.001	-0.242	-0.104	0.09	0.124	0.381	0.386	0.605	-0.127	0.495	-0.103	1
		0.793	0.991	0.994	0.175	0.563	0.617	0.492	0.029	0.027	0	0.481	0.003	0.568	0