Circulating Cytokines and Lymphocyte Subsets in Patients Who Have Recovered from COVID-19

Table 5

Correlation analysis between lymphocyte subsets and cytokines in HCs.

Analyses		Cytokines (pg/mL)							Lymphocyte subsets (per/μL)
		IL-2	IL-4	IL-6	IL-10	TNF-α	INF-γ	IL-17	Total lymphocyte	CD3^+ T cell	CD3^+CD4^+ T cell	CD3^+CD8^+ T cell	CD19^+ B cell	CD56^+ NK cell	CD4^+/CD8^+
IL-2		1	-0.086	0.093	0.472	0.333	0.599	0.6	0.005	-0.018	0.149	0.037	-0.236	0.096	-0.012
		0	0.665	0.637	0.011	0.083	0.001	0.001	0.982	0.928	0.451	0.851	0.227	0.626	0.951
IL-4		-0.086	1	-0.103	-0.045	0.151	-0.135	0.031	-0.006	0.167	-0.17	-0.016	-0.351	-0.248	-0.015
		0.665	0	0.601	0.821	0.444	0.494	0.877	0.975	0.394	0.387	0.934	0.067	0.204	0.94
IL-6		0.093	-0.103	1	-0.021	-0.046	0.092	-0.187	0.053	-0.068	0.335	-0.319	-0.007	0.138	0.445
		0.637	0.601	0	0.916	0.817	0.64	0.34	0.787	0.73	0.081	0.097	0.971	0.482	0.018
IL-10		0.472	-0.045	-0.021	1	0.24	0.53	0.332	-0.229	-0.345	-0.382	-0.245	-0.026	0.132	0.006
		0.011	0.821	0.916	0	0.218	0.004	0.085	0.242	0.072	0.045	0.21	0.896	0.504	0.977
TNF-α		0.333	0.151	-0.046	0.24	1	0.446	0.486	-0.12	-0.192	0.036	-0.34	-0.043	0.002	0.407
		0.083	0.444	0.817	0.218	0	0.017	0.009	0.544	0.328	0.857	0.077	0.83	0.99	0.032
INF-γ		0.599	-0.135	0.092	0.53	0.446	1	0.387	0.064	-0.14	-0.042	-0.141	-0.129	0.351	0.056
		0.001	0.494	0.64	0.004	0.017	0	0.042	0.748	0.478	0.833	0.475	0.513	0.067	0.778
IL-17		0.6	0.031	-0.187	0.332	0.486	0.387	1	0.062	0.125	0.08	0.235	0.014	-0.062	-0.142
		0.001	0.877	0.34	0.085	0.009	0.042	0	0.755	0.526	0.685	0.229	0.945	0.755	0.47
Total lymphocyte		0.005	-0.006	0.053	-0.229	-0.12	0.064	0.062	1	0.757	0.598	0.666	0.498	0.53	-0.398
		0.982	0.975	0.787	0.242	0.544	0.748	0.755	0	0	0.001	0	0.007	0.004	0.036
CD3^+ T cell		-0.018	0.167	-0.068	-0.345	-0.192	-0.14	0.125	0.757	1	0.629	0.819	0.316	-0.104	-0.499
		0.928	0.394	0.73	0.072	0.328	0.478	0.526	0	0	0	0	0.101	0.597	0.007
CD3^+CD4^+ T cell		0.149	-0.17	0.335	-0.382	0.036	-0.042	0.08	0.598	0.629	1	0.336	0.375	0.036	0.172
		0.451	0.387	0.081	0.045	0.857	0.833	0.685	0.001	0	0	0.081	0.05	0.854	0.382
CD3^+CD8^+ T cell		0.037	-0.016	-0.319	-0.245	-0.34	-0.141	0.235	0.666	0.819	0.336	1	0.31	0.025	-0.806
		0.851	0.934	0.097	0.21	0.077	0.475	0.229	0	0	0.081	0	0.108	0.9	0
CD19^+ B cell		-0.236	-0.351	-0.007	-0.026	-0.043	-0.129	0.014	0.498	0.316	0.375	0.31	1	0.226	-0.067
		0.227	0.067	0.971	0.896	0.83	0.513	0.945	0.007	0.101	0.05	0.108	0	0.247	0.734
CD56^+ NK cell		0.096	-0.248	0.138	0.132	0.002	0.351	-0.062	0.53	-0.104	0.036	0.025	0.226	1	-0.08
		0.626	0.204	0.482	0.504	0.99	0.067	0.755	0.004	0.597	0.854	0.9	0.247	0	0.685
CD4^+/CD8^+		-0.012	-0.015	0.445	0.006	0.407	0.056	-0.142	-0.398	-0.499	0.172	-0.806	-0.067	-0.08	1
		0.951	0.94	0.018	0.977	0.032	0.778	0.47	0.036	0.007	0.382	0	0.734	0.685	0