Circular RNA cir-ITCH Is a Potential Therapeutic Target for the Treatment of Castration-Resistant Prostate Cancer

Figure 1

AR expression is not expressed in PC-3 cells. cir-ITCH downregulated the protein expression level of β-catenin, p-AKT, and p-mTOR in LNCaP cells and PC-3 cells as seen with western blot. The expression of representative proteins in PC-3 cells was not affected by exogenous androgen or androgen receptor antagonist.