Evaluation of Grewia ferruginea Hochst ex A. Rich Mucilage as Suspending Agent in Metronidazole Benzoate Suspension

Table 1

Formulation ingredients of the metronidazole benzoate suspensions.

Formula	MB	GFM	SCMC	XGM	MP	PP	T-80	PG	SO	SS	S	DW
	%	%	%	%	%	%	%	%	%	%	%	%
	FA1	4	0.5	—	—	0.18	0.02	0.1	2	30	0.07	15	100
FA2	4	1	—	—	0.18	0.02	0.1	2	30	0.07	15	100
FA3	4	1.5	—	—	0.18	0.02	0.1	2	30	0.07	15	100
FA4	4	2	—	—	0.18	0.02	0.1	2	30	0.07	15	100
FB1	4	—	0.5	—	0.18	0.02	0.1	2	30	0.07	15	100
FB2	4	—	1	—	0.18	0.02	0.1	2	30	0.07	15	100
FB3	4	—	1.5	—	0.18	0.02	0.1	2	30	0.07	15	100
FB4	4	—	2	—	0.18	0.02	0.1	2	30	0.07	15	100
FC1	4	—	—	0.5	0.18	0.02	0.1	2	30	0.07	15	100
FC2	4	—	—	1	0.18	0.02	0.1	2	30	0.07	15	100
FC3	4	—	—	1.5	0.18	0.02	0.1	2	30	0.07	15	100
FC4	4	—	—	2	0.18	0.02	0.1	2	30	0.07	15	100

Key: MB: metronidazole benzoate; MP: methyl paraben; PP: propyl paraben; T-80: Tween 80; PG: propylene glycol; SO: sorbitol solution (70%); SS: sodium saccharine; S: sucrose; DW: distilled water; XGM: xanthan gum; GFM: Grewia ferruginea mucilage; and SCMC: sodium carboxymethyl cellulose; FA for GFM, FB for SCMC, and FC for XGM.