The Impact of the NOD2/CARD15 Variant (3020insC) and PSMA6 Polymorphism (-8C>G) on the Development and Outcome of Multiple Myeloma

Table 3

Hardy-Weinberg equilibrium (HWE) for PSMA6 and NOD2/CARD15 variants in the case and control groups according to expected (E) and observed (O) values.

Groups	Genotypes			Total	HWE value and
PSMA6 gene
—	CC	CG	GG	—	—
Control
E	84.64	14.72	0.64	100	,
O	84	16	0	100
Case
E	81	18	1	100	,
O	81	18	1	100
NOD2/CARD15 gene
—	Wild-type homozygotes	Heterozygotes	3020insC homozygotes	—	—
Control
E	96.04	3.92	0.04	100	,
O	96	4	0	100
Case
E	92.16	7.68	0.16	100	,
O	92	8	0	100

If and the corresponding , then the population is in HWE.