The Impact of the NOD2/CARD15 Variant (3020insC) and PSMA6 Polymorphism (-8C>G) on the Development and Outcome of Multiple Myeloma

Table 7

Multivariate Cox analysis in the survival of MM patients.

Variable	Multivariate Cox analysis for OS			Multivariate Cox analysis for PFS
	value	HR	95% CI	value	HR	95% CI
ISS
I+II	—	Reference	—	—	Reference	—
III	0.42	1.18	0.77-1.82	0.01	1.57	1.11-2.21
Auto-HSCT
Yes	—	Reference	—	—	Reference	—
No	0.01	3.82	1.36-10.78	0.14	1.72	0.82-3.61
PSMA6
CC	—	Reference	—	—	Reference	—
CG+GG	0.86	1.42	0.02-82.33	0.41	5.18	0.095-281.82
NOD2/CARD15
Wild type	—	Reference	—	—	Reference	—
Mutated

Too small group for analysis.