Repairing and Analgesic Effects of Umbilical Cord Mesenchymal Stem Cell Transplantation in Mice with Spinal Cord Injury

Figure 9

Histological comparison of the spinal cord tissue in each group. (a) The gray matter in the spinal cord of the (A, B) model group was unclear. The vacuolar necrosis was observed, the nerve fibers were relatively sparse and chaotic, and there were different degrees of inflammatory cell infiltration. In the (C, D) treatment group, the inflammatory cells infiltrated decreased, and the nerve fibers passed through the spinal cord injury area of mice. H.E. staining. Scale bars: 50 μm. (b) Immunohistochemical staining for inflammatory cell identification of CD15 (mouse monoclonal anti-CD15, 1 : 350, Abcam) in sections of mouse spinal cord. Note that a more intense CD15-positive cell (arrowhead) response was shown in the (A) model group, but poor CD15-positive cell (arrowhead) response at or proximal to the zone of injury in the (B) treatment group. Scale bars: 100 μm.

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