Research Article
The Prognostic Values of the Insulin-Like Growth Factor Binding Protein Family in Ovarian Cancer
Table 2
The prognostic value of the IGFBP2 mRNA expression in ovarian cancer.
| | Overall survival | Progression-free survival | Cases | HR (95% CI) | value | Cases | HR (95% CI) | value |
| Histology | | | | | | | All cancer patients | 1656 | 1.13 (0.99−1.29) | 0.081 | 1435 | 1.17 (1.03−1.33) | 0.014 | Serous cancer patients | 1207 | 0.87 (0.74−1.02) | 0.079 | 1104 | 1.13 (0.98−1.3) | 0.098 | Endometrioid cancer patients | 37 | 4.93 (0.55−44.16) | 0.11 | 51 | 2.67 (1.05− 6.79) | 0.032 | Pathological grades | | | | | | | I | 56 | 0.55 (0.22−1.42) | 0.21 | 37 | 1.76 (0.58−5.41) | 0.31 | II | 324 | 1.31 (0.95−1.8) | 0.096 | 256 | 1.21 (0.9−1.63) | 0.2 | III | 1015 | 0.86 (0.73−1.02) | 0.088 | 837 | 1.07 (0.91−1.27) | 0.41 | Clinical stages | | | | | | | I and II | 135 | 1.68 (0.77−3.67) | 0.19 | 163 | 2.16 (1.1−4.25) | 0.022 | III and IV | 1220 | 1.11 (0.95−1.28) | 0.18 | 1081 | 0.91 (0.78−1.07) | 0.27 | Chemotherapy | | | | | | | Contains platin | 1409 | 1.2 (1.03−1.39) | 0.02 | 1259 | 1.12 (0.98−1.27) | 0.087 | Contains taxol | 793 | 1.16 (0.95−1.41) | 0.16 | 715 | 0.91 (0.75−1.11) | 0.35 | Contains taxol+platin | 776 | 1.15 (0.94−1.41) | 0.17 | 698 | 1.08 (0.91−1.29) | 0.38 |
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