Research Article
The Prognostic Values of the Insulin-Like Growth Factor Binding Protein Family in Ovarian Cancer
Table 3
The prognostic value of the IGFBP3 mRNA expression in ovarian cancer.
| | Overall survival | Progression-free survival | Cases | HR (95% CI) | value | Cases | HR (95% CI) | value |
| Histology | | | | | | | All cancer patients | 1656 | 1.25 (1.08−1.44) | 0.0031 | 1435 | 0.89 (0.77−1.03) | 0.13 | Serous cancer patients | 1207 | 1.25 (1.05−1.48) | 0.0099 | 1104 | 0.88 (0.75−1.05) | 0.15 | Endometrioid cancer patients | 37 | 5.91 (0.66−52.98) | 0.071 | 51 | 0.34 (0.12−0.95) | 0.031 | Pathological grades | | | | | | | I | 56 | 0.59 (0.23−1.53) | 0.28 | 37 | 2.67 (0.89−7.96) | 0.068 | II | 324 | 1.36 (1.01−1.84) | 0.045 | 256 | 0.81 (0.58−1.13) | 0.22 | III | 1015 | 0.88 (0.74−1.03) | 0.12 | 837 | 0.83 (0.68−1.01) | 0.062 | Clinical stages | | | | | | | I and II | 135 | 1.56 (0.72−3.4) | 0.26 | 163 | 0.59 (0.31−1.14) | 0.12 | III and IV | 1220 | 1.2 (1.02−1.41) | 0.028 | 1081 | 0.89 (0.75−1.05) | 0.15 | Chemotherapy | | | | | | | Contains platin | 1409 | 1.21 (1.04−1.41) | 0.014 | 1259 | 1.12 (0.99−1.28) | 0.078 | Contains taxol | 793 | 1.15 (0.94−1.4) | 0.17 | 715 | 0.82 (0.67−1) | 0.049 | Contains taxol+platin | 776 | 1.13 (0.92−1.38) | 0.24 | 698 | 0.8 (0.65−0.98) | 0.029 |
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