Research Article
The Prognostic Values of the Insulin-Like Growth Factor Binding Protein Family in Ovarian Cancer
Table 4
The prognostic value of the IGFBP4 mRNA expression in ovarian cancer.
| | Overall survival | Progression-free survival | Cases | HR (95% CI) | value | Cases | HR (95% CI) | value |
| Histology | | | | | | | All cancer patients | 1656 | 1.14 (0.99−1.3) | 0.068 | 1435 | 0.94 (0.83−1.06) | 0.32 | Serous cancer patients | 1207 | 1.17 (1−1.37) | 0.047 | 1104 | 1.24 (1.07−1.44) | 0.005 | Endometrioid cancer patients | 37 | 2.81 (0.31−25.11) | 0.34 | 51 | 0.1 (0.01−0.79) | 0.0077 | Pathological grades | | | | | | | I | 56 | 0.19 (0.03−1.47) | 0.076 | 37 | 0.24 (0.05−1.09) | 0.045 | II | 324 | 1.41 (1.04−1.92) | 0.026 | 256 | 1.52 (1.11−2.09) | 0.0085 | III | 1015 | 1.18 (0.98−1.42) | 0.08 | 837 | 1.23 (1−1.5) | 0.045 | Clinical stages | | | | | | | I and II | 135 | 1.47 (0.67−3.21) | 0.33 | 163 | 0.34 (0.19−0.6) | 8.7e−05 | III and IV | 1220 | 1.16 (0.99−1.35) | 0.065 | 1081 | 1.34 (1.15−1.56) | 0.00015 | Chemotherapy | | | | | | | Contains platin | 1409 | 1.24 (1.06−1.44) | 0.0067 | 1259 | 1.1 (0.96−1.27) | 0.17 | Contains taxol | 793 | 1.15 (0.95−1.4) | 0.15 | 715 | 1.21 (1.02−1.45) | 0.029 | Contains taxol+platin | 776 | 1.18 (0.97−1.43) | 0.1 | 698 | 1.23 (1.03−1.47) | 0.022 |
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