The Prognostic Values of the Insulin-Like Growth Factor Binding Protein Family in Ovarian Cancer

Table 6

The prognostic value of the IGFBP6 mRNA expression in ovarian cancer.

	Overall survival			Progression-free survival
	Cases	HR (95% CI)	value	Cases	HR (95% CI)	value
Histology
All cancer patients	1656	1.19 (1.05−1.35)	0.0079	1435	1.2 (1.04−1.39)	0.011
Serous cancer patients	1207	1.27 (1.09−1.49)	0.0023	1104	1.29 (1.12−1.49)	0.00046
Endometrioid cancer patients	37	0.32 (0.05−1.92)	0.19	51	1.76 (0.58−5.35)	0.31
Pathological grades
I	56	1.48 (0.55−3.96)	0.43	37	2.68 (0.9−7.98)	0.066
II	324	1.29 (0.95−1.74)	0.097	256	1.7 (1.22−2.39)	0.0017
III	1015	1.27 (1.06−1.53)	0.0084	837	1.31 (1.11−1.54)	0.0015
Clinical stages
I and II	135	0.53 (0.24−1.18)	0.11	163	1.42 (0.8−2.53)	0.23
III and IV	1220	1.14 (0.98−1.33)	0.082	1081	1.26 (1.09−1.45)	0.0015
Chemotherapy
Contains platin	1409	1.21 (1.05−1.39)	0.0069	1259	1.12 (0.96−1.3)	0.15
Contains taxol	793	1.17 (0.97−1.41)	0.1	715	1.27 (1.05−1.53)	0.012
Contains taxol+platin	776	1.13 (0.93−1.37)	0.21	698	1.26 (1.05−1.53)	0.015

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