Research Article

Influence of Geographical and Seasonal Variations on Carbazole Alkaloids Distribution in Murraya koenigii: Deciding Factor of Its In Vitro and In Vivo Efficacies against Cancer Cells

Table 5

Regional variation of mahanine, mahanimbine, and koenimbine in different MEFs.

Region of leaf collectionYield: a gram of MEF/100 g of dry leafMahanine (%)Mahanimbine (%)Koenimbine (%)

Jammu (MEFJ)6.4 ± 0.59.3 ± 1.627.0 ± 2.56.3 ± 1.2
Bihar (MEFB)5.8 ± 0.22.7 ± 1.312.0 ± 1.57.3 ± 1.4
Madhya Pradesh (MEFMP)7.2 ± 0.15.0 ± 0.98.6 ± 0.91.2 ± 0.9
West Bengal (MEFWB)5.5 ± 0.514.0 ± 0.820.7 ± 1.211.9 ± 1.1
Goa (MEFG)6.5 ± 0.633.0 ± 2.96.3 ± 0.9ND
Maharashtra (MEFM)5.9 ± 0.134.0 ± 2.710.0 ± 1.1ND
Andhra Pradesh (MEFAP)5.9 ± 0.2523.0 ± 4.19.2 ± 0.9ND
Tamil Nadu (MEFTN)9.0 ± 0.743.0 ± 2.58.3 ± 1.70.8 ± 0.3
Kerala (MEFK)8.0 ± 0.535 ± 4.06.3 ± 1.2ND

The yield of all MEFs (mahanine-enriched fractions) and their markers as obtained from HPLC. ND: not detected. A representative profile of these alkaloids in leaflet collected during one year has been tabulated. These data were derived from three individual experiments, and mean ± SD was indicated.