Influence of Geographical and Seasonal Variations on Carbazole Alkaloids Distribution in Murraya koenigii: Deciding Factor of Its In Vitro and In Vivo Efficacies against Cancer Cells
Table 5
Regional variation of mahanine, mahanimbine, and koenimbine in different MEFs.
Region of leaf collection
Yield: a gram of MEF/100 g of dry leaf
Mahanine (%)
Mahanimbine (%)
Koenimbine (%)
Jammu (MEFJ)
6.4 ± 0.5
9.3 ± 1.6
27.0 ± 2.5
6.3 ± 1.2
Bihar (MEFB)
5.8 ± 0.2
2.7 ± 1.3
12.0 ± 1.5
7.3 ± 1.4
Madhya Pradesh (MEFMP)
7.2 ± 0.1
5.0 ± 0.9
8.6 ± 0.9
1.2 ± 0.9
West Bengal (MEFWB)
5.5 ± 0.5
14.0 ± 0.8
20.7 ± 1.2
11.9 ± 1.1
Goa (MEFG)
6.5 ± 0.6
33.0 ± 2.9
6.3 ± 0.9
ND
Maharashtra (MEFM)
5.9 ± 0.1
34.0 ± 2.7
10.0 ± 1.1
ND
Andhra Pradesh (MEFAP)
5.9 ± 0.25
23.0 ± 4.1
9.2 ± 0.9
ND
Tamil Nadu (MEFTN)
9.0 ± 0.7
43.0 ± 2.5
8.3 ± 1.7
0.8 ± 0.3
Kerala (MEFK)
8.0 ± 0.5
35 ± 4.0
6.3 ± 1.2
ND
The yield of all MEFs (mahanine-enriched fractions) and their markers as obtained from HPLC. ND: not detected. A representative profile of these alkaloids in leaflet collected during one year has been tabulated. These data were derived from three individual experiments, and mean ± SD was indicated.