Research Article

17-Allylamino-demethoxygeldanamycin Used Alone or in Combination with Sodium Orthovanadate Promotes Apoptosis and Inhibits Invasion of SH-SY5Y Cells by Modulating PIWIL2

Figure 3

5 μM 17-AAG, 5 μM SOV, and the mixture of 5 μM (17-AAG+SOV) reduce the expression of antiapoptotic protein at 72 h. (a) Western blot analysis of PIWIL2 and Bcl-xl protein level in SH-SY5Y cells. β-Actin was the loading control. (b) The bar graph showed the of the ratio interest proteins/β-actin band intensity obtained by pooling the results from 3 independent experiments in SH-SY5Y cells, respectively (, , ).
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