Identification of a Seven-lncRNA Immune Risk Signature and Construction of a Predictive Nomogram for Lung Adenocarcinoma

Figure 1

Flowchart of our study. Gene expression profiles were downloaded from The Cancer Genome Atlas (TCGA) database. Immune-related genes were extracted from the Molecular Signatures Database. Immune-related lncRNAs were identified according to Pearson’s correlation. The training set was used to identify immune-related prognostic lncRNAs and establish a risk signature based on the immune-related prognostic lncRNAs. The prognosis analysis was validated by the validation set and the combination set, respectively. A nomogram was constructed by including the immune-related lncRNA signature and other prognosis-related clinical features in the training set and confirmed by the validation set and the combination set, respectively. Functional enrichment analyses based on the training set were utilized to explore immune-related functions. ROC: receiver operating characteristic.