Identification of a Seven-lncRNA Immune Risk Signature and Construction of a Predictive Nomogram for Lung Adenocarcinoma

Table 5

Representative results of Gene Set Enrichment Analysis.

Group	Name	Size	NES	NOM value	FDR value
High-risk group	KEGG_BASE_EXCISION_REPAIR	35	1.901	0.013	0.025
	KEGG_CELL_CYCLE	124	2.381	<0.001	<0.001
	KEGG_MISMATCH_REPAIR	23	2.091	<0.001	0.005
	KEGG_NUCLEOTIDE_EXCISION_REPAIR	44	2.139	<0.001	0.003
	KEGG_p53_SIGNALING_PATHWAY	68	1.787	0.006	0.045
Low-risk group	KEGG_ABC_TRANSPORTERS	44	-1.647	0.014	0.111
	KEGG_JAK_STAT_SIGNALING_PATHWAY	155	-1.783	0.012	0.060
	KEGG_mTOR_SIGNALING_PATHWAY	52	-1.528	0.020	0.160
	GO_NEGATIVE_REGULATION_OF_IMMUNE_RESPONSE	140	-1.920	0.002	0.068
	GO_NEGATIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS	118	-1.920	0.004	0.067
	GO_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE	160	-1.860	0.010	0.076
	GO_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS	447	-1.850	0.002	0.075
	GO_T_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	99	-1.840	0.013	0.072
	GO_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE	30	-1.780	0.004	0.084
	GO_NEGATIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE	36	-1.760	0.008	0.089
	GO_REGULATION_OF_T_HELPER_17_TYPE_IMMUNE_RESPONSE	19	-1.700	0.027	0.105
	GO_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	175	-1.620	0.045	0.125
	IMMUNE_RESPONSE	234	-1.836	0.020	0.020
	IMMUNE_SYSTEM_PROCESS	331	-1.914	0.016	0.016

NES: normalized enrichment score; FDR: false discovery rate; KEGG: Kyoto Encyclopedia of Genes and Genomes; GO: Gene Ontology; ABC: ATP-binding cassette; mTOR: mammalian target of rapamycin.