Research Article
Protection of Lycopene against Embryonic Anomalies and Yolk Sac Placental Vasculogenic Disorders Induced by Nicotine Exposure
Figure 4
Lycopene regulates the expressions of growth factors in yolk sac placentas exposed to nicotine. (a) Hif-1α mRNA expression levels. (b) IGF-1 mRNA expression levels. (c) α-SMA mRNA expression levels. (d, e) mRNA expression levels of VEGF-α and TGF-β1, respectively. (f, g) Western blot analyses of VEGF-α and TGF-β1, respectively. The mRNA and protein values were normalized with GAPDH expression. Data represents . Lycopene cotreated groups were compared with control (a) and nicotine (b) groups for significance ().
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