Inhibition of Wilms’ Tumor Proliferation and Invasion by Blocking TGF-β Receptor I in the TGF-β/Smad Signaling Pathway

Table 1

Correlation analysis between TGF-β1 and P-smad2/3 expression and the clinicopathological characteristics of Wilms’ tumor in 60 patients.

Characteristics	Total number ()	TGF-β1		^2	value	P-smad2/3		^2	value
		Positive	Negative			Positive	Negative
Age
0-3	39	24	15	0.155	0.694	17	22	0.003	0.956
>3	21	14	7			9	12
Gender
Boys	35	21	14	0.402	0.526	15	20	0.008	0.930
Girls	25	17	8			11	14
Pathology
FH	47	30	17	0.023	0.879	19	28	0.747	0.387
uFH	13	8	5			7	6
Clinic stage
I-II	22	10	12	4.781	0.012	5	17	6.007	0.014
III-IV	38	28	10			21	17
Metastasis or invasion
Yes	24	19	5	4.381	0.038	16	8	8.869	0.003
No	36	19	17			10	26