Research Article

A Novel Schizophrenia Diagnostic Model Based on Statistically Significant Changes in Gene Methylation in Specific Brain Regions

Table 4

DNA methylation sites in GSE89706 for constructing the SCZ diagnostic model.

Probe IDGenomic positionGeneGene region valuelogFC

cg11676382chr22:51142802–51143308SHANK3Body0.031–0.012
cg06304401NLGN15′UTR0.030–0.007
cg19510409NLGN1Body0.0160.017
cg15078211chr7:42267546–42267823GLI35′UTR0.011–0.014
cg17390350chr7:42267546–42267823GLI35′UTR0.002–0.048
cg22411165GLI3Body0.002–0.020
cg10518481chr19:5339640–5341061PTPRSTSS15000.0020.026
cg04250837chr1:231762414–231763115TSNAX-DISC1Body0.0410.019
cg07007152chr7:155601175–155603235SHHBody0.0140.015
cg15244043chr7:155604725–155605095SHHBody0.0070.011
cg20521696chr7:155601175–155603235SHHBody0.0290.030

FC, fold change; TSS1500, transcription start site 1500; 5′UTR, 5′ untranslated region.