Machine Learning Analysis of Image Data Based on Detailed MR Image Reports for Nasopharyngeal Carcinoma Prognosis

Table 2

All important imaging higher ranked imaging findings.

ID	Variables	Numbers	5 years surv		Important
OS
1	Jugular foramen	770/22	89.32/53.13	<0.001	1.000
2	Paranasal sinuses	695/97	90.63/71.70	<0.001	0.966
3	Central necrosis of retropharyngeal LNs	696/96	89.58/78.75	0.002	0.893
4	Steep hill	494/298	92.08/81.96	<0.001	0.891
5	Meninges	764/28	89.57/48.05	<0.001	0.791
6	Invasion of carotid sheath	655/137	90.16/79.47	0.001	0.666
7	Extracapsular invasion of cervical LNs	735/57	89.09/77.70	0.002	0.630
8	Number of lower cervical LNs	0∼11	—	<0.001	0.488
9	Bilateral of parapharyngeal space	691/101	89.96/76.36	<0.001	0.336
10	Number of retropharyngeal LNs	0∼6	—	0.002	0.332
11	Pressure of carotid sheath	775/17	88.43/80.00	0.075	0.327
12	Number of upper cervical LNs	0∼23	—	<0.001	0.256
13	Posterior nasal meatus invasion	648/144	89.96/80.61	<0.001	0.205
DMFS
1	Number of cervical LNs	0∼34	—	<0.001	1.000
2	Meninges	764/28	88.81/51.63	<0.001	0.462
3	Posterior nasal meatus invasion	648/144	90.01/77.16	<0.001	0.396
4	Bilateral of retropharyngeal LNs	575/217	91.14/78.30	<0.001	0.387
5	Infratemporal fossa	771/21	88.61/52.84	<0.001	0.386
6	Extracapsular invasion of cervical LNs	735/57	88.45/78.19	0.007	0.250
7	Central necrosis of retropharyngeal LNs	696/96	88.97/78.49	0.002	0.242
8	Medial cartilage of ear	315/477	90.73/85.69	0.034	0.234
9	Musculus longus colli	513/279	91.24/81.06	<0.001	0.231
10	Jugular foramen	770/22	88.43/62.20	<0.001	0.204
11	Sphenoid sinus	700/92	89.51/74.02	<0.001	0.197
12	Number of upper cervical LNs	0∼23	—	<0.001	0.182
LRFS
1	Clustering of LNs	602/190	91.18/83.08	0.003	1.000
2	Pharyngeal recess	61/731	97.83/88.65	0.058	0.817
3	Paranasal sinuses	695/97	91.37/74.03	<0.001	0.765
4	Central necrosis of retropharyngeal LNs	600/192	91.02/83.98	0.004	0.540
5	Jugular foramen	770/22	90.03/64.62	<0.001	0.531
6	Bilateral of cervical LNs	317/475	93.85/86.11	0.001	0.366
7	Bilateral of retropharyngeal LNs	575/217	91.89/82.07	<0.001	0.309
8	Tensor velum palatine muscle	366/426	92.82/86.27	0.005	0.293
9	Bone of ear	755/37	89.83/79.78	0.038	0.193
10	Pressure of carotid sheath	775/17	89.70/72.51	0.033	0.145
11	Infratemporal fossa	771/21	89.78/72.96	0.012	0.137

: log-rank; LNs = lymph nodes; number (none/yes or invasion); HR (—) for continue variables; important (standardize): while 1.000 is the most important. Variables are selected by mRMR.