High-Fat Diet Induced Hedgehog Signaling Modifications during Chronic Kidney Damage

Figure 5

Microphotographs of (a) hematoxylin and eosin-stained renal sections of control and treated groups D-1 and D-2. Glomerular edema (➱) and tubular necrosis (yellow rightwards arrow) can be noted in the D-1 renal section, while hypocellularity (❱) and shrinkage of glomeruli (⬅) marked the histological changes in D-2 and (b) of Masson’s trichrome stained renal sections of control and treated groups D-1 and D-2. Blue color along the glomerular capsule ▲) is an indication of the collagen deposition in both study groups. (D-1 = Murine model fed on high-fat diet 1; D-2 = Murine model fed on high-fat diet 2). (Magnification; i: 100x; ii: 400x).

(a)

(b)