HAND2-AS1 Works as a ceRNA of miR-3118 to Suppress Proliferation and Migration in Breast Cancer by Upregulating PHLPP2

Figure 3

HAND2-AS1 restricted the process of BC by inhibiting miR-3118. (a, b) CCK8 and colony formation assays were performed to measure cell proliferation ability in cells transfected with pcDNA3.1/HAND2-AS1 and miR-3118 mimics. (c) The rate of flow cytometry analysis was set up to estimate the apoptosis rate. (d, e) Transwell assays were conducted to determine abilities of cell migration and invasion. (f) Western blot was carried out to evaluate the relevant proteins of the EMT process.

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