The Actions and Mechanisms of P2X7R and p38 MAPK Activation in Mediating Bortezomib-Induced Neuropathic Pain

<div>IL-1<i>β</i>, IL-6, and TNF-<i>α</i> mRNA expression in DRG and SDH after inhibition of P2X7R. (a) DRG IL-1<i>β</i> mRNA. (b) DRG IL-6 mRNA. (c) DRG TNF-<i>α</i> mRNA. (d) SDH IL-1<i>β</i> mRNA. (e) SDH IL-6 mRNA. 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BioMed Research International

fig4

Figure 4

Figure 4: The Actions and Mechanisms of P2X7R and p38 MAPK Activation in Mediating Bortezomib-Induced Neuropathic Pain 