PBMCs to Stress-Associated miR-18a-5p and miR-22-3p Ratios as New Indicators of Metabolic Syndrome
Table 4
The risk of inflammatory cells to miRNA ratios for MetS.
Models
OR (95% CI)
value
LT18R
Univariate model
2.5 (1.6–3.7)
<0.001
Binary model 1
3.8 (1.9, 7.7)
<0.001
Binary model 2
2.8 (1.0, 7.5)
0.049
LT22R
Univariate model
1.3 (1.1–1.6)
0.003
Binary model 1
1.2 (1.0, 1.5)
0.03
Binary model 2
1.5 (1.0, 2.2)
0.093
MT18R
Univariate model
61.6 (9.1–417.2)
<0.001
Binary model 1
279.3 (14.1, 5533.6)
<0.001
Binary model 2
510.6 (1.0, 279892.1)
0.053
MT22R
Univariate model
3.4 (1.5–7.9)
0.005
Binary model 1
2.9 (1.2, 7.2)
0.022
Binary model 2
6.2 (0.5, 73.6)
0.151
PT18R
Univariate model
2.1 (1.4–3.0)
<0.001
Binary model 1
3.1 (1.7, 5.6)
<0.001
Binary model 2
2.5 (1.0, 6.0)
0.047
PT22R
Univariate model
1.3 (1.1–1.5)
0.003
Binary model 1
1.2 (1.0, 1.4)
0.03
Binary model 2†
1.4 (0.9, 2.0)
0.094
Legend: this table shows the logistic regression analysis for the risk of inflammatory cells to miRNA ratios for MetS. value calculated without any adjustment. value adjusted for age, gender, and physical activity. Further adjustment for WC based on model 1. Abbreviations: LT18R: lymphocyte to miR-18a-5p ratio; LT22R: lymphocyte to miR-22-3p ratio; MT18R: monocyte to miR-18a-5p ratio; MT22R: monocyte to miR-22-3p ratio; PT18R: PBMCs to miR-18a-5p ratio; PT22R: PBMCs to miR-22-3p ratio; OR: odds ratio; CI: confidence interval.
