Research Article

PBMCs to Stress-Associated miR-18a-5p and miR-22-3p Ratios as New Indicators of Metabolic Syndrome

Table 5

Spearman correlation among the miRNAs, inflammatory cells, stress hormones, and HOMA-IR.

CortisolIL-6TNF-αHOMA-IR

Total subjects
 miR-18a-5p-0.304-0.073-0.1650.052
 miR-22-3p-0.139-0.290-0.3670.199
 LC0.4820.2150.170-0.576
 MC0.1370.148-0.0740.269
MetS group
 miR-18a-5p0.1330.2120.0940.037
 miR-22-3p-0.124-0.217-0.1950.141
 LC0.1620.0070.0780.159
 MC-0.0910.1640.046-0.004
Control group
 miR-18a-5p-0.086-0.0750.008-0.474
 miR-22-3p0.186-0.127-0.276-0.246
 LC0.5180.1680.3150.323
 MC0.198-0.100-0.1950.084

Legend: , . Abbreviations: IL-6: interleukin-6; TNF-α: tumor necrosis factor-α, HOMA-IR: homoeostasis model assessment of insulin; LC: lymphocyte count; MC: monocyte count.