Research Article
PBMCs to Stress-Associated miR-18a-5p and miR-22-3p Ratios as New Indicators of Metabolic Syndrome
Table 5
Spearman correlation among the miRNAs, inflammatory cells, stress hormones, and HOMA-IR.
| | Cortisol | IL-6 | TNF-α | HOMA-IR |
| Total subjects | | | | | miR-18a-5p | -0.304 | -0.073 | -0.165 | 0.052 | miR-22-3p | -0.139 | -0.290 | -0.367 | 0.199 | LC | 0.482 | 0.215 | 0.170 | -0.576 | MC | 0.137 | 0.148 | -0.074 | 0.269 | MetS group | | | | | miR-18a-5p | 0.133 | 0.212 | 0.094 | 0.037 | miR-22-3p | -0.124 | -0.217 | -0.195 | 0.141 | LC | 0.162 | 0.007 | 0.078 | 0.159 | MC | -0.091 | 0.164 | 0.046 | -0.004 | Control group | | | | | miR-18a-5p | -0.086 | -0.075 | 0.008 | -0.474 | miR-22-3p | 0.186 | -0.127 | -0.276 | -0.246 | LC | 0.518 | 0.168 | 0.315 | 0.323 | MC | 0.198 | -0.100 | -0.195 | 0.084 |
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Legend: , . Abbreviations: IL-6: interleukin-6; TNF- α: tumor necrosis factor- α, HOMA-IR: homoeostasis model assessment of insulin; LC: lymphocyte count; MC: monocyte count. |