Research Article

PPAR-γ Mediates Ta-VNS-Induced Angiogenesis and Subsequent Functional Recovery after Experimental Stroke in Rats

Figure 6

Inhibition of PPAR-γ suppresses the ta-VNS-mediated promotion of BDNF, VEGF, and P-eNOS expression at 28 d after MCAO/R. (a) Representative western blot images of VEGF and BDNF expression in the peri-infarct cortex. (b, c) Quantitative results from (a). (d) The bar graph reflected VEGF mRNA expression in each group. (e) The bar graph reflected BDNF mRNA expression in each group. (f) ELISA assay for P-eNOS protein expression ( vs sham+LV-control group, vs I/R group+LV-control, and vs I/R+ta-VNS+LV-control group).