Research Article
Uncovering PD-L1 and CD8+ TILS Expression and Clinical Implication in Cervical Squamous Cell Carcinoma
Table 2
The relationship between PD-L1/CD8+ TILS density groups and clinicopathological features.
| | Clinicopathological features | | A group | B group | C group | D group | |
| | Age (years) | | | | | | | | ≤47 | 51 | 13 (25.5) | 19 (37.3) | 17 (33.3) | 2 (3.9) | 0.473 | | >47 | 44 | 8 (18.2) | 21 (47.7) | 10 (22.7) | 5 (11.4) | | | Tumor size (cm) | | | | | | | | ≤3 | 51 | 7 (13.7) | 18 (35.3) | 21 (41.2) | 5 (9.8) | 0.473 | | >3 | 44 | 14 (31.8) | 22 (50.0) | 6 (13.6) | 2 (4.5) | | | Depth of interstitial infiltration (cm) | | | | | | | | <1/2 | 29 | 2 (6.9) | 9 (31.0) | 13 (44.8) | 5 (17.2) | 0.001 | | ≥1/2 | 66 | 19 (28.8) | 31 (47.0) | 14 (21.2) | 2 (3.0) | | | FIGO stage | | | | | | | | I~II | 77 | 19 (24.7) | 25 (32.5) | 26 (33.8) | 7 (9.1) | 0.001 | | III~IV | 18 | 2 (11.1) | 15 (83.3) | 1 (5.6) | 0 (0.0) | | | Degree of differentiation | | | | | | | | Moderately high differentiation | 76 | 19 (25.0) | 26 (34.2) | 25 (32.9) | 6 (7.9) | 0.001 | | Low differentiation | 19 | 2 (10.5) | 14 (73.7) | 2 (10.5) | 1 (5.3) | | | Vascular invasion | | | | | | | | No | 48 | 7 (14.6) | 18 (37.5) | 16 (33.3) | 7 (14.6) | 0.918 | | Yes | 47 | 14 (29.8) | 22 (46.8) | 11 (23.4) | 0 (0.0) | | | Lymph node metastasis | | | | | | | | No | 69 | 15 (21.7) | 21 (30.4) | 26 (37.7) | 7 (10.1) | 0.006 | | Yes | 26 | 6 (23.1) | 19 (73.1) | 1 (3.8) | 0 (0.0) | |
|
|
