Overexpression of NNT-AS1 Activates TGF-β Signaling to Decrease Tumor CD4 Lymphocyte Infiltration in Hepatocellular Carcinoma

Table 2

Cox’s proportional hazards model analyses of the association between NNT-AS1 and overall survival.

Variables	Univariate analysis		Multivariate analysis
	HR (95% CI)	value	HR (95% CI)	value
NNT-AS1 (low vs. high)	1.918 (1.017-3.619)	0.044	1.701 (0.694-4.167)	0.245
Sex (female vs. male)	1.335 (0.321-5.546)	0.691
Age (≤60 vs. >60)	0.734 (0.348-1.549)	0.471
Tumor size (≤5 cm vs. >5 cm)	2.071 (1.082-3.962)	0.028	1.932 (0.738-5.056)	0.180
Tumor number (single vs. multiple)	1.198 (0.367-3.915)	0.765
Pathological grade (H, M vs. L)	2.053 (0.838-5.029)	0.116	1.540 (0.568-4.178)	0.396
TNM stage (I vs. II, III)	2.113 (1.049-4.255)	0.036	2.806 (1.052-7.481)	0.039

CI: confidence interval; HR: hazard ratio.