Research Article

Overexpression of NNT-AS1 Activates TGF-β Signaling to Decrease Tumor CD4 Lymphocyte Infiltration in Hepatocellular Carcinoma

Table 3

IHC staining for TGF-β, TGFBR1, SMAD1/5/9, and CD4 in HCC tissue samples.

ScoreTGF-βTGFBR1SMAD1/5/9CD4
Normal ()Cancer ()Normal ()Cancer ()Normal ()Cancer ()Normal ()Cancer ()

-5 (31.25%)001 (6.25%)9 (56.25%)1 (6.25%)1 (6.25%)3 (18.75%)
+9 (56.25%)11 (68.75%)13 (81.25%)7 (43.75%)7 (43.75%)2 (12.50%)2 (12.50%)5 (31.25%)
++2 (12.50%)4 (12.50%)2 (12.50%)6 (37.50%)011 (68.75%)6 (37.50%)8 (50.00%)
+++01 (6.26%)1 (6.26%)2 (12.50%)02 (12.50%)7 (43.75%)0
value0.0460.0050.0080.002