PRDX2 Promotes the Proliferation and Metastasis of Non-Small Cell Lung Cancer In Vitro and In Vivo
Knockdown of PRDX2 inhibits proliferation, migration, and invasion in A549 cells. (a) A549 cells were transfected with scrambled control shRNA or two PRDX2 shRNAs and followed using the qRT-PCR assay to measure the mRNA levels of PRDX2. (b) Western blot assay was used to check the protein levels of PRDX2. (c) Cell viability was performed by CCK8 assay. (d) Migration assay was performed using Transwell assay without Matrigel gel, and invasion assay was performed using Transwell assay with Matrigel gel. ;;.
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