Research Article
Pharmacokinetic Study of Thirteen Ingredients after the Oral Administration of Flos Chrysanthemi Extract in Rats by UPLC-MS/MS
Table 2
Calibration curves, correlation coefficients, linear ranges, and LLOQ of the 13 analytes.
| | Compounds | Calibration curves | Correlation coefficients () | Linear range (ng/mL) | LLOQ (ng/mL) |
| | Luteolin | | 0.9964 | 20.0-4000.0 | 0.1 | | Cynaroside | | 0.9937 | 20.0-4000.0 | 0.1 | | Luteolin 7-O-glucuronide | | 0.9927 | 10.0-2000.0 | 2.0 | | Isochlorogenic acid C | | 0.9919 | 5.0-1000.0 | 5.0 | | Cryptochlorogenic acid | | 0.9990 | 5.0-1000.0 | 5.0 | | Chlorogenic acid | | 0.9943 | 5.0-1000.0 | 0.2 | | Apigenin | | 0.9993 | 5.0-1000.0 | 0.2 | | Acacetin | | 0.9984 | 5.0-1000.0 | 0.1 | | Hyperoside | | 0.9953 | 5.0-1000.0 | 0.2 | | Isoquercitrin | | 0.9958 | 5.0-1000.0 | 0.2 | | Apigenin 7-glucoside | | 0.9989 | 5.0-1000.0 | 0.1 | | Tilianin | | 0.9924 | 1.0-200.0 | 0.1 | | Hesperidin | | 0.9975 | 1.0-200.0 | 1.0 |
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