Screening and Identification of Differentially Expressed Genes Expressed among Left and Right Colon Adenocarcinoma

Table 3

GO and KEGG pathway enrichment analyses of hub genes between left and right COAD.

Term	Description	Count in gene set	value
GO:0006919	Activation of cysteine-type endopeptidase activity involved in apoptotic process	3	8.50E − 04
GO:0097296	Activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	2	0.007
GO:0031648	Protein destabilization	2	0.019
GO:0070534	Protein K63-linked ubiquitination	2	0.020
GO:0006955	Immune response	3	0.020
GO:0043235	Receptor complex	3	0.002
GO:0005887	Integral component of plasma membrane	5	0.003
GO:0005886	Plasma membrane	7	0.006
GO:0005829	Cytosol	6	0.013
GO:0042802	Identical protein binding	5	4.05E − 04
GO:0019789	SUMO transferase activity	2	0.009
GO:0031625	Ubiquitin protein ligase binding	3	0.010
GO:0005515	Protein binding	9	0.026
GO:d0002039	p53 binding	2	0.035
hsa05200	Pathways in cancer	7	8.51E − 07
hsa04520	Adherens junction	3	0.003
hsa04110	Cell cycle	3	0.008
hsa04068	FoxO signaling pathway	3	0.010
hsa05205	Proteoglycans in cancer	3	0.021

GO: Gene Ontology; KEGG: Kyoto Encyclopaedia of Genes and Genomes; DEGs: differentially expressed genes; COAD: colon adenocarcinoma.