Overexpression of MicroRNA-16 Alleviates Atherosclerosis by Inhibition of Inflammatory Pathways

<div>Verification of potential target genes (PDCD4) of miR-16 from mRNA and protein expression levels. (a) The expressions of miR-16 were measured by real-time PCR in vessel tissues of ApoE-/- mice after treatment with agomir control and agomir-16. (b) The relative expressions of PDCD4 were measured by real-time PCR in vessel tissues of ApoE-/- mice after treatment with agomir control and agomir-16. (c) Immunohistochemical analyses of PDCD4 expression in aortic lesion of ApoE-/- mice after treatment with the agomiR control and agomiR-16. (d) Semiquantitative results for immunohistochemical results. (e) Western blot results of PDCD4 expression in two groups. 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BioMed Research International

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Figure 4

Figure 4: Overexpression of MicroRNA-16 Alleviates Atherosclerosis by Inhibition of Inflammatory Pathways 