Overexpression of MicroRNA-16 Alleviates Atherosclerosis by Inhibition of Inflammatory Pathways
Table 3
Correlation of miR-16 expression with clinical characteristics in CAD patients.
Variable
High expression ()
Lower expression ()
value
Age
0.825
0.364
≥63
10 (66.7)
13 (52.0)
<63
5 (33.3)
12 (48.0)
BMI
3.536
0.060
≥26.69
10 (66.7)
9 (36.0)
<26.69
5 (33.3)
16 (64.0)
Current smoking
0.008
0.931
Yes
10 (66.7)
17 (68.0)
No
5 (33.3)
8 (32.0)
Hypertension
0.036
0.850
Yes
12 (80.0)
18 (72.0)
No
3 (20.0)
7 (28.0)
DM
3.546
0.060
Yes
8 (53.3)
6 (24.0)
No
7 (46.7)
19 (76.0)
PLT (109/L)
0.444
0.505
≥207
5 (33.3)
11 (44.0)
<207
10 (66.7)
14 (56.0)
Cr (μmol/L)
0.107
0.744
≥76.7
7 (46.7)
13 (52.0)
<76.7
8 (53.3)
12 (48.0)
ALT (U/L)
0.178
0.673
≥17.8
5 (33.3)
10 (40.0)
<17.8
10 (66.7)
15 (60.0)
AST (U/L)
1.153
0.283
≥19.4
8 (53.3)
9 (36.0)
<19.4
7 (46.7)
16 (64.0)
TC (mmol/L)
1.504
0.220
≥4.31
9 (60.0)
10 (40.0)
<4.31
6 (40.0)
15 (60.0)
TG (mmol/L)
0.264
0.608
≥2.06
6 (40.0)
8 (32.0)
<2.06
9 (60.0)
17 (68.0)
HDL-C (mmol/L)
0.107
0.744
≥1.04
8 (53.3)
12 (48.0)
<1.04
7 (46.7)
13 (52.0)
LDL-C (mmol/L)
1.504
0.220
≥2.95
9 (60.0)
10 (40.0)
<2.95
6 (40.0)
15 (60.0)
LVEF (%)
0.444
0.505
≥61
8 (53.3)
16 (64.0)
<61
7 (46.7)
9 (36.0)
CAD: coronary artery disease; BMI: body mass index; DM: diabetes mellitus; PLT: blood platelet; Cr: creatinine; ALT: alanine aminotransferase; AST: aspartate transaminase; TC: total cholesterol; TG: total glyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; LVEF: left ventricular ejection fractions. Data are presented as the number (%). .
